Impact of drinking polluted water on the human microbiota and pathogenic bacteria

UMR 7267 EBI Laboratory - Poitiers
 

Water quality in the Nouvelle-Aquitaine region, where almost two-thirds of water bodies do not meet the standards set out in the Water Framework Directive, as a result of various alterations caused by human activities. The presence of chemical compounds from human activities contributes to the deterioration of water quality and presents potential health risks. The MICROPOL project is part of the "One health" concept and aims to demonstrate the possibility that water pollution promotes infectious bacterial diseases and disrupts the human intestinal microbiota.

To do this, it plans to map drinking water pollution in Grand-Poitiers, study the impact of water pollution on the human intestinal microbiota and also the impact of water pollution on the survival, virulence and establishment of human pathogenic bacteria in the intestinal microbiota. Several techniques will be used in this project: anaerobic culture, PCR, qPCR, biofilm, motility, cell infection, mass spectrometry, GC-MS, etc.